O Programa de Pós-Graduação em Biociências da UERJ e o Programa de Oncobiologia promoverão, em outubro, dia 5, um curso online dedicado à plataforma de bioinformática Xena (Visualizing and interpreting cancer genomics data via the Xena platform. Goldman MJ, et al. Nat Biotechnol. 2020 Jun; 38(6): 675-678. doi: 10.1038/s41587-020-0546-8).
O evento requer inscrição, que pode ser realizada até ao dia 22 de setembro, através do link: (https://forms.gle/5BzYoCv2yUKNVhEa6).
Seguem mais detalhes abaixo.
We invite you to the UCSC Xena Workshop! UCSC Xena is a platform for visualizing and analyzing cancer genomic data, including data from The Cancer Genome Atlas (TCGA) and normal samples (Gtex).
Abstract: UCSC Xena (http://xena.ucsc.edu/) is a web-based visual integration and exploration tool for multi-omic data and associated clinical and phenotypic annotations. Xena showcases seminal cancer genomics datasets from TCGA and the Pan-Cancer Atlas, as well as the GDC, PCAWG, and ICGC; a total of more than 1500 datasets across 50 cancer types. We support virtually any type of functional genomics data modality, including SNPs, INDELs, large structural variants, CNV, gene and other types of expression, DNA methylation, clinical and phenotypic annotations. Browser features include the high-performance Visual Spreadsheet, dynamic Kaplan-Meier survival analysis, genome-wide differential gene expression analysis, genome-wide GSEA analysis, powerful filtering and subgrouping, charts, statistical analyses, genomic signatures, and live bookmarks. Researchers can use the same visualizations to view their own data privately and securely in Xena. * Is the over-expression of a specific gene associated with lower survival in a certain cancer type?
* Is this gene differentially expressed in TCGA tumor vs GTEx normal?
* What are the most differentially expressed genes for the subgroups I have chosen?
* What is the relationship between expression, mutation, copy number, etc for a specific gene?
For more information, visit: https://xena.ucsc.edu/public/. Speaker: Dr. Mary Goldman - UCSC (University of California, Santa Cruz) The event will be online and free, on October 5th (1pm - 4pm). Register using the form until September 22nd (https://forms.gle/5BzYoCv2yUKNVhEa6) We wait for you!